African Green Monkey Dermal Fibroblasts
African Green Monkey primary cells (Chlorocebus sabaeus) isolated using validated methods. Available fresh or cryopreserved with viability guarantee. Contact us for cell-specific specifications.
African Green Monkey Dermal Fibroblasts Overview
African Green Monkey Dermal Fibroblasts are primary fibroblasts isolated from African green monkey (Chlorocebus sabaeus) skin tissue. Dermal fibroblasts are key mediators of extracellular matrix production, wound repair, and tissue remodeling.
Common Applications
- Wound healing and tissue repair assays
- Fibrosis research and anti-fibrotic drug screening
- iPSC reprogramming from primary fibroblasts
- Collagen synthesis and ECM remodeling studies
Product Details
Cells are isolated from dermal tissue by enzymatic digestion and cryopreserved at early passage. Each lot ships with a Certificate of Analysis documenting viability and donor information.
About the African Green Monkey
Chlorocebus sabaeus
African green monkeys are increasingly important in biomedical research, particularly for infectious disease studies.
Natural hosts for SIV without disease progression, they provide unique insights into viral pathogenesis and represent a valuable model for respiratory virus research.
Human Similarity
~93% genetic homology with extensive immune receptor cross-reactivity
Global Availability
Multiple geographic origins with established breeding colonies
Regulatory Accepted
FDA & EMA preferred species for biologics safety assessment
Origin Lineages at a Glance
Primary Research Areas
Immunotoxicology Studies
Assess potential immunotoxic effects of drug candidates on immune cell populations and function.
Vaccine Development
Evaluate immunogenicity and T cell responses to vaccine antigens in preclinical models.
CAR-T & Cell Therapy Research
Source material for developing and testing chimeric antigen receptor constructs and adoptive cell therapies.
Cytokine Release Assays
Screen biologics for potential cytokine release syndrome risk using species-relevant immune cells.
Flow Cytometry & Immunophenotyping
Characterize immune cell subset distributions and surface marker expression profiles.
ADCC & CDC Assays
Evaluate antibody-dependent and complement-dependent cytotoxicity of therapeutic antibodies.
| Species | African Green Monkey (Chlorocebus sabaeus) |
|---|---|
| Cell Type | Dermal Fibroblasts |
| Cell Count | ≥10 × 10⁶ viable cells per vial (standard) |
| Viability (Fresh) | ≥90% |
| Viability (Post-Thaw) | ≥70% |
| Viability Method | Trypan blue exclusion or flow cytometry |
| Format | Fresh or cryopreserved |
| Cryopreservation Medium | Fibroblast medium (DMEM + 10% FBS) with 10% DMSO |
| Isolation Method | Enzymatic digestion (collagenase) of dermis tissue or explant culture outgrowth |
| Storage (Cryopreserved) | Liquid nitrogen vapor phase |
| Shipping (Fresh) | Ambient temperature, overnight delivery |
| Shipping (Cryopreserved) | Dry ice |
| Donor Information | Age, sex, and health status available |
| Testing | Pathogen-free per supplier SOPs |
Geographic Origins Guide
Select the optimal origin for your research requirements
Caribbean Origin ★ MOST COMMON
island
St. Kitts-derived populations with well-documented lineages. Excellent for controlled studies.
African Origin
mainland
Wild-caught or first-generation captive from African source populations.
Need help selecting an origin?
Our scientific team can advise on the optimal origin for your study design and regulatory requirements.
Primary cells are typically provided at passage 0 (P0) or passage 1 (P1) unless otherwise specified. Low-passage cells retain tissue-specific phenotype and function. Higher passage cells are available on request for applications where passage number is less critical.
Culture conditions vary by cell type. We provide cell-type-specific culture medium recommendations and handling protocols with each order. In general, primary cells require specialized media with appropriate growth factors and supplements. Contact us for detailed protocols.
Thaw rapidly at 37°C, transfer into pre-warmed cell-type-specific medium. Plate immediately onto appropriate substrate (collagen, fibronectin, or gelatin coating as appropriate). Change medium after 24 hours to remove DMSO and non-adherent cells.
Post-thaw viability is typically ≥70% for cryopreserved primary cells. Plating efficiency and time to confluence vary by cell type. Fresh cells generally provide the best plating efficiency and are recommended for sensitive applications.
Yes. Donor demographics (age, sex, health status) and tissue source details are available. Custom tissue dissection and cell isolation can be arranged. Matched sets from the same donor are available on request.