Cynomolgus Monkey Aqueous Humor - Donor
Cynomolgus Monkey biological fluid sample (Macaca fascicularis) collected under controlled conditions. Processed promptly for optimal quality. Contact us for specifications and availability.
Cynomolgus Monkey Aqueous Humor - Donor Overview
Cynomolgus Monkey Aqueous Humour - Donor is research-grade cynomolgus macaque aqueous humor sample intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information and handling details to support consistency across studies.
Common applications
- Preclinical and translational research
- Assay development and validation
- Biomarker studies
- Method development
Collection, processing & handling
Samples are collected and processed using standardized protocols appropriate to the sample type. Packaging and shipping are configured for temperature-controlled logistics to preserve sample integrity for your specific workflow requirements.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Ordering notes
For specific donor criteria, source, volumes, or custom handling requirements, request a quote and include your study specifications. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
About the Cynomolgus Monkey
Macaca fascicularis
The cynomolgus macaque is the most widely used non-human primate in biomedical research, valued for its close physiological and immunological similarity to humans.
With over 60% genetic homology for key immune receptors, cynomolgus monkeys provide highly translatable data for drug development, making them ideal for immunology, infectious disease, and toxicology studies.
Human Similarity
~93% genetic homology with extensive immune receptor cross-reactivity
Global Availability
Multiple geographic origins with established breeding colonies
Regulatory Accepted
FDA & EMA preferred species for biologics safety assessment
Origin Lineages at a Glance
Primary Research Areas
Ocular Drug Development
Measure drug concentrations and metabolites in the anterior chamber for ocular pharmacokinetic (PK) studies.
Glaucoma & IOP Research
Study intraocular pressure regulation, aqueous humor dynamics, and outflow pathway mechanisms.
Blood-Aqueous Barrier Studies
Assess barrier integrity and permeability changes in response to inflammation, surgery, or drug treatment.
Ocular Immunology
Evaluate immune privilege, inflammatory mediators (cytokines, chemokines), and immune cell markers in the anterior segment.
Ocular Biomarker Discovery
Identify and validate novel protein, metabolite, or lipid biomarkers for anterior segment diseases including uveitis and cataract.
| Species | Cynomolgus Monkey (Macaca fascicularis) |
|---|---|
| Sample Type | Aqueous Humor |
| Collection Method | Anterior chamber paracentesis using a 27-30G needle under anesthesia |
| Appearance | Clear and colorless |
| Typical Yield | 50-200 µL per eye |
| Volume Options | 50 µL, 100 µL, pooled |
| Contamination Control | Visual inspection for blood or fibrin; samples with visible contamination excluded |
| Processing | Centrifuged to remove cellular debris, aliquoted within 1 hour of collection |
| Storage Temperature | '-80°C |
| Shipping | Dry ice |
| Donor Information | Age, sex, and health status available |
Geographic Origins Guide
Select the optimal origin for your research requirements
Chinese Origin ★ MOST COMMON
mainland
Chinese-origin cynomolgus are no longer exported by China. Cynomolgus macaques are not native to China and were historically imported from Cambodia, Vietnam, Laos, and Indonesia. Current samples are sourced from US breeding colonies established from China-line imports.
Mauritian Origin ★ DEFINED GENETICS
island
Mauritian cynomolgus have limited MHC diversity due to founder effects, making them valuable for immunology studies requiring genetic consistency.
Cambodian Origin ★ SOUTHEAST ASIAN
mainland
Cambodian-origin animals offer a Southeast Asian source with genetics that have not been mixed with other country lineages in the same way seen in some China-line populations.
Vietnamese Origin ★ SOUTHEAST ASIAN
mainland
Vietnamese cynomolgus provide another Southeast Asian option for programs that require distinct lineage sourcing or supply chain diversification.
Indonesian Origin ★ ISLAND ORIGIN
island
Indonesian-origin cynomolgus were among the earliest origins used in preclinical research and represented one of the largest research populations before China entered the market.
Philippine Origin ★ ISLAND ORIGIN
island
Philippine-origin cynomolgus were one of the first origins used broadly in research, with a long history as a trusted and widely used model.
Need help selecting an origin?
Our scientific team can advise on the optimal origin for your study design and regulatory requirements.
Aqueous humor is collected via anterior chamber paracentesis using a fine-gauge needle (27-30G) under general anesthesia. The procedure is performed by trained veterinary ophthalmologists using a surgical microscope. Typical recovery time is rapid, and repeated collections are possible with appropriate intervals.
Typical yield is 50-200 µL per eye depending on species. Larger primates (cynomolgus, rhesus) yield more than smaller species (marmoset). Both eyes can be sampled if study design permits, and pooled samples are available on request.
Aqueous humor is evaluated for clarity (clear, colorless) and absence of visible blood or fibrin contamination. Samples with visible contamination are excluded from standard inventory. Protein content and cell count data are available upon request for specialized applications.