Cynomolgus Monkey Gastric and Intestine Fluid
Cynomolgus Monkey biological fluid sample (Macaca fascicularis) collected under controlled conditions. Processed promptly for optimal quality. Contact us for specifications and availability.
Cynomolgus Monkey Gastric and Intestine Fluid Overview
Cynomolgus Monkey Gastric and Intestine Fluid is research-grade cynomolgus macaque gastric and intestinal fluid intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information and handling details to support consistency across studies.
Common applications
- Preclinical and translational research
- Assay development and validation
- Biomarker studies
- Method development
Collection, processing & handling
Samples are collected and processed using standardized protocols appropriate to the sample type. Packaging and shipping are configured for temperature-controlled logistics to preserve sample integrity for your specific workflow requirements.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Ordering notes
For specific donor criteria, source, volumes, or custom handling requirements, request a quote and include your study specifications. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
About the Cynomolgus Monkey
Macaca fascicularis
The cynomolgus macaque is the most widely used non-human primate in biomedical research, valued for its close physiological and immunological similarity to humans.
With over 60% genetic homology for key immune receptors, cynomolgus monkeys provide highly translatable data for drug development, making them ideal for immunology, infectious disease, and toxicology studies.
Human Similarity
~93% genetic homology with extensive immune receptor cross-reactivity
Global Availability
Multiple geographic origins with established breeding colonies
Regulatory Accepted
FDA & EMA preferred species for biologics safety assessment
Origin Lineages at a Glance
Primary Research Areas
Oral Drug Formulation & Dissolution
Study drug dissolution, stability, and absorption in physiologically relevant GI fluids for oral formulation development.
GI Pharmacokinetics
Measure drug and metabolite concentrations across GI segments to characterize regional absorption and first-pass metabolism.
GI Barrier & Permeability Research
Evaluate intestinal barrier function, tight junction integrity, and permeability markers in preclinical GI models.
Microbiome & Metabolomics
Analyze bile acids, short-chain fatty acids, and microbial metabolites in GI fluid for gut microbiome research.
GI Toxicology
Assess GI-specific toxicity biomarkers and inflammatory mediators for oral drug safety studies.
| Species | Cynomolgus Monkey (Macaca fascicularis) |
|---|---|
| Sample Type | Gastric and Intestinal Fluid |
| Collection Method | Endoscopic aspiration, nasogastric intubation, or necropsy collection under anesthesia |
| Appearance | Variable; gastric fluid is clear to slightly yellow; intestinal fluid may be yellow-green |
| Typical Yield | 2-20 mL per collection (region and method-dependent) |
| Volume Options | 1 mL, 5 mL, 10 mL |
| GI Region | Gastric, duodenal, jejunal, ileal, or colonic fluid (specify at order) |
| Processing | Collected into protease inhibitor tubes on request; centrifuged and aliquoted within 1 hour |
| Storage Temperature | '-80°C |
| Shipping | Dry ice |
| Donor Information | Age, sex, fasting status, and health status available |
Geographic Origins Guide
Select the optimal origin for your research requirements
Chinese Origin ★ MOST COMMON
mainland
Chinese-origin cynomolgus are no longer exported by China. Cynomolgus macaques are not native to China and were historically imported from Cambodia, Vietnam, Laos, and Indonesia. Current samples are sourced from US breeding colonies established from China-line imports.
Mauritian Origin ★ DEFINED GENETICS
island
Mauritian cynomolgus have limited MHC diversity due to founder effects, making them valuable for immunology studies requiring genetic consistency.
Cambodian Origin ★ SOUTHEAST ASIAN
mainland
Cambodian-origin animals offer a Southeast Asian source with genetics that have not been mixed with other country lineages in the same way seen in some China-line populations.
Vietnamese Origin ★ SOUTHEAST ASIAN
mainland
Vietnamese cynomolgus provide another Southeast Asian option for programs that require distinct lineage sourcing or supply chain diversification.
Indonesian Origin ★ ISLAND ORIGIN
island
Indonesian-origin cynomolgus were among the earliest origins used in preclinical research and represented one of the largest research populations before China entered the market.
Philippine Origin ★ ISLAND ORIGIN
island
Philippine-origin cynomolgus were one of the first origins used broadly in research, with a long history as a trusted and widely used model.
Need help selecting an origin?
Our scientific team can advise on the optimal origin for your study design and regulatory requirements.
GI fluid is collected via endoscopic aspiration under general anesthesia for live collections, or via direct aspiration from specific GI segments at necropsy. Nasogastric intubation can be used for gastric fluid. The method is selected based on the GI region of interest and study design.
Volume depends on the GI region and collection method. Gastric aspirates typically yield 5-20 mL. Small intestinal fluid yields vary (2-10 mL per segment). Fasting status significantly affects volume and composition. Custom collection protocols can be arranged.
GI fluid is evaluated for color, pH, and absence of food contamination (fasting samples preferred for most applications). Protease inhibitors are added on request to preserve protein integrity. Collection region, fasting status, and pH are documented.
