Cynomolgus Monkey Lipemic Serum
High-quality Cynomolgus Monkey serum (Macaca fascicularis) with minimal hemolysis and lipemia. Collected, processed, and stored under controlled conditions. Ideal for immunoassays, clinical chemistry, and biomarker studies.
The Cynomolgus Monkey
Macaca fascicularis
The cynomolgus macaque is the most widely used non-human primate in biomedical research, valued for its close physiological and immunological similarity to humans.
With over 60% genetic homology for key immune receptors, cynomolgus monkeys provide highly translatable data for drug development, making them ideal for immunology, infectious disease, and toxicology studies.
Human Similarity
~93% genetic homology with extensive immune receptor cross-reactivity
Global Availability
Multiple geographic origins with established breeding colonies
Regulatory Accepted
FDA & EMA preferred species for biologics safety assessment
Geographic Origins
Common Research Applications
Cynomolgus Monkey Lipemic Serum is research-grade cynomolgus macaque serum intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information and handling details to support consistency across studies.
Serum provides a protein-rich, cell-free matrix ideal for immunoassays, antibody detection, and clinical chemistry applications.
Common applications
- ELISA and multiplex immunoassay panels
- Clinical chemistry and metabolic profiling
- Antibody titer and serological testing
- Protein biomarker quantification
- PK/PD and dose-response studies
Collection, processing & handling
Serum is processed from clotted blood using consistent separation practices optimized for immunoassay and clinical chemistry applications. Packaging and shipping are configured for frozen logistics to preserve biomarker integrity.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Also available: matched plasma samples for comparative biomarker analysis from the same species for comprehensive study design.
Ordering notes
For specific donor criteria, source, volumes, or custom handling requirements, request a quote and include your study specifications. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
Clinical Chemistry Panels
Measure biochemical parameters including liver enzymes, kidney function markers, and metabolic indicators.
Immunoassay Development
Develop and validate ELISAs, Luminex assays, and other immunoassays in species-specific matrix.
Biomarker Validation
Validate circulating protein, metabolite, or nucleic acid biomarkers in relevant species.
Pharmacokinetic Analysis
Quantify drug and metabolite concentrations for PK modeling and dose optimization.
Antibody Titer Determination
Measure humoral immune responses and antibody levels in vaccine and immunology studies.
Matrix Interference Testing
Assess assay performance and interference in species-specific serum matrix.
| Species | Cynomolgus Monkey (Macaca fascicularis) |
|---|---|
| Sample Type | Serum |
| Collection | No anticoagulant, clotted |
| Clot Time | 30-60 minutes at room temperature |
| Processing | Centrifuged at 2000 × g for 10 minutes |
| Hemolysis Index | Non-hemolyzed or as specified |
| Lipemia Index | Non-lipemic or as specified |
| Volume Options | 0.5 mL, 1 mL, 5 mL, or custom |
| Storage Temperature | '-20°C or -80°C |
| Shipping | Dry ice |
| Freeze-Thaw | Avoid repeated freeze-thaw cycles |
| Donor Information | Age, sex, and health status available |
Geographic Origins Guide
Select the optimal origin for your research requirements
Chinese Origin ★ MOST COMMON
mainland
Chinese-origin cynomolgus are no longer exported by China. Cynomolgus macaques are not native to China and were historically imported from Cambodia, Vietnam, Laos, and Indonesia. Current samples are sourced from US breeding colonies established from China-line imports.
Mauritian Origin ★ DEFINED GENETICS
island
Mauritian cynomolgus have limited MHC diversity due to founder effects, making them valuable for immunology studies requiring genetic consistency.
Cambodian Origin ★ SOUTHEAST ASIAN
mainland
Cambodian-origin animals offer a Southeast Asian source with genetics that have not been mixed with other country lineages in the same way seen in some China-line populations.
Vietnamese Origin ★ SOUTHEAST ASIAN
mainland
Vietnamese cynomolgus provide another Southeast Asian option for programs that require distinct lineage sourcing or supply chain diversification.
Indonesian Origin ★ ISLAND ORIGIN
island
Indonesian-origin cynomolgus were among the earliest origins used in preclinical research and represented one of the largest research populations before China entered the market.
Philippine Origin ★ ISLAND ORIGIN
island
Philippine-origin cynomolgus were one of the first origins used broadly in research, with a long history as a trusted and widely used model.
Need help selecting an origin?
Our scientific team can advise on the optimal origin for your study design and regulatory requirements.
Serum is obtained from clotted blood without anticoagulant, lacking clotting factors. Plasma is obtained from anticoagulated blood and contains clotting factors. Choose serum for most immunoassays and clinical chemistry; choose plasma for coagulation studies or when clotting factors are relevant.
Store at -20°C for short-term (weeks) or -80°C for long-term storage. Avoid repeated freeze-thaw cycles as this can degrade proteins and affect assay results. Aliquot into single-use volumes upon receipt.
Lipemic serum appears cloudy due to high lipid content, which can interfere with certain assays. Hemolyzed serum has red discoloration from lysed red blood cells. We offer both normal and intentionally lipemic/hemolyzed samples for matrix interference testing.