Cynomolgus Monkey Placental Pericytes
Cynomolgus Monkey primary cells (Macaca fascicularis) isolated using validated methods. Available fresh or cryopreserved with viability guarantee. Contact us for cell-specific specifications.
Cynomolgus Monkey Placental Pericytes Overview
Cynomolgus Monkey Placental Pericytes is research-grade cynomolgus macaque placental pericytes intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information and handling details to support consistency across studies.
Placental tissue enables maternal-fetal interface research, drug transfer studies, and developmental toxicology.
Common applications
- Maternal-fetal drug transfer
- Placental barrier function
- Developmental toxicology
- Pregnancy complication research
- Transplacental transport
Collection, processing & handling
Tissue is collected and processed with protocols designed to preserve downstream histology and molecular workflows. Available formats include fresh, frozen, OCT-embedded, or FFPE as appropriate. Cold-chain logistics with documented handling throughout.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Ordering notes
For specific donor criteria, source, volumes, or custom handling requirements, request a quote and include your study specifications. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
About the Cynomolgus Monkey
Macaca fascicularis
The cynomolgus macaque is the most widely used non-human primate in biomedical research, valued for its close physiological and immunological similarity to humans.
With over 60% genetic homology for key immune receptors, cynomolgus monkeys provide highly translatable data for drug development, making them ideal for immunology, infectious disease, and toxicology studies.
Human Similarity
~93% genetic homology with extensive immune receptor cross-reactivity
Global Availability
Multiple geographic origins with established breeding colonies
Regulatory Accepted
FDA & EMA preferred species for biologics safety assessment
Origin Lineages at a Glance
Primary Research Areas
Immunotoxicology Studies
Assess potential immunotoxic effects of drug candidates on immune cell populations and function.
Vaccine Development
Evaluate immunogenicity and T cell responses to vaccine antigens in preclinical models.
CAR-T & Cell Therapy Research
Source material for developing and testing chimeric antigen receptor constructs and adoptive cell therapies.
Cytokine Release Assays
Screen biologics for potential cytokine release syndrome risk using species-relevant immune cells.
Flow Cytometry & Immunophenotyping
Characterize immune cell subset distributions and surface marker expression profiles.
ADCC & CDC Assays
Evaluate antibody-dependent and complement-dependent cytotoxicity of therapeutic antibodies.
| Species | Cynomolgus Monkey (Macaca fascicularis) |
|---|---|
| Cell Type | Placental Pericytes |
| Cell Count | ≥10 × 10⁶ viable cells per vial (standard) |
| Viability (Fresh) | ≥90% |
| Viability (Post-Thaw) | ≥70% |
| Viability Method | Trypan blue exclusion or flow cytometry |
| Format | Fresh or cryopreserved |
| Cryopreservation Medium | Pericyte growth medium with 10% DMSO |
| Isolation Method | Enzymatic digestion (collagenase) of placental tissue; immunomagnetic selection for pericyte markers (NG2/PDGFRβ) |
| Storage (Cryopreserved) | Liquid nitrogen vapor phase |
| Shipping (Fresh) | Ambient temperature, overnight delivery |
| Shipping (Cryopreserved) | Dry ice |
| Donor Information | Age, sex, and health status available |
| Testing | Pathogen-free per supplier SOPs |
Geographic Origins Guide
Select the optimal origin for your research requirements
Chinese Origin ★ MOST COMMON
mainland
Chinese-origin cynomolgus are no longer exported by China. Cynomolgus macaques are not native to China and were historically imported from Cambodia, Vietnam, Laos, and Indonesia. Current samples are sourced from US breeding colonies established from China-line imports.
Mauritian Origin ★ DEFINED GENETICS
island
Mauritian cynomolgus have limited MHC diversity due to founder effects, making them valuable for immunology studies requiring genetic consistency.
Cambodian Origin ★ SOUTHEAST ASIAN
mainland
Cambodian-origin animals offer a Southeast Asian source with genetics that have not been mixed with other country lineages in the same way seen in some China-line populations.
Vietnamese Origin ★ SOUTHEAST ASIAN
mainland
Vietnamese cynomolgus provide another Southeast Asian option for programs that require distinct lineage sourcing or supply chain diversification.
Indonesian Origin ★ ISLAND ORIGIN
island
Indonesian-origin cynomolgus were among the earliest origins used in preclinical research and represented one of the largest research populations before China entered the market.
Philippine Origin ★ ISLAND ORIGIN
island
Philippine-origin cynomolgus were one of the first origins used broadly in research, with a long history as a trusted and widely used model.
Need help selecting an origin?
Our scientific team can advise on the optimal origin for your study design and regulatory requirements.
Primary cells are typically provided at passage 0 (P0) or passage 1 (P1) unless otherwise specified. Low-passage cells retain tissue-specific phenotype and function. Higher passage cells are available on request for applications where passage number is less critical.
Culture conditions vary by cell type. We provide cell-type-specific culture medium recommendations and handling protocols with each order. In general, primary cells require specialized media with appropriate growth factors and supplements. Contact us for detailed protocols.
Thaw rapidly at 37°C, transfer into pre-warmed cell-type-specific medium. Plate immediately onto appropriate substrate (collagen, fibronectin, or gelatin coating as appropriate). Change medium after 24 hours to remove DMSO and non-adherent cells.
Post-thaw viability is typically ≥70% for cryopreserved primary cells. Plating efficiency and time to confluence vary by cell type. Fresh cells generally provide the best plating efficiency and are recommended for sensitive applications.
Yes. Donor demographics (age, sex, health status) and tissue source details are available. Custom tissue dissection and cell isolation can be arranged. Matched sets from the same donor are available on request.
