Cynomolgus Monkey Plasma
Cynomolgus Monkey plasma (Macaca fascicularis) available with multiple anticoagulant options. Processed promptly after collection for optimal quality. Suitable for coagulation studies, PK analysis, and biomarker research.
The Cynomolgus Monkey
Macaca fascicularis
The cynomolgus macaque is the most widely used non-human primate in biomedical research, valued for its close physiological and immunological similarity to humans.
With over 60% genetic homology for key immune receptors, cynomolgus monkeys provide highly translatable data for drug development, making them ideal for immunology, infectious disease, and toxicology studies.
Human Similarity
~93% genetic homology with extensive immune receptor cross-reactivity
Global Availability
Multiple geographic origins with established breeding colonies
Regulatory Accepted
FDA & EMA preferred species for biologics safety assessment
Geographic Origins
Common Research Applications
Cynomolgus Monkey Plasma (Export) is research-grade cynomolgus macaque plasma intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information and handling details to support consistency across studies.
Plasma preserves coagulation factors and circulating biomarkers, providing an optimal matrix for pharmacokinetic studies and protein-based assays.
Common applications
- Pharmacokinetic (PK) and toxicokinetic (TK) studies
- Biomarker discovery and validation
- Cytokine and chemokine profiling
- Coagulation and hemostasis research
- Metabolomics and lipidomics workflows
Collection, processing & handling
Plasma is processed with documented anticoagulant (K2EDTA, Li-heparin, or citrate) and centrifugation conditions. Single or double-spin processing available. Packaging and shipping are configured for frozen or refrigerated logistics as appropriate to your workflow.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Also available: matched serum or whole blood samples from the same species for comprehensive study design.
Ordering notes
For specific donor criteria, source, volumes, or custom handling requirements, request a quote and include your study specifications. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
Coagulation Factor Analysis
Measure clotting factors and assess drug effects on coagulation cascades.
Pharmacokinetic Studies
Quantify drug concentrations in plasma for ADME characterization.
Biomarker Research
Identify and measure circulating biomarkers preserved in anticoagulated samples.
Protein Binding Studies
Determine plasma protein binding characteristics of drug candidates.
Metabolomics
Profile metabolite changes in response to disease or treatment.
Lipidomics
Characterize lipid profiles and changes in lipid metabolism.
| Species | Cynomolgus Monkey (Macaca fascicularis) |
|---|---|
| Sample Type | Plasma |
| Anticoagulant Options | K2-EDTA, Sodium Heparin, Sodium Citrate |
| Processing | Centrifuged at 2000 × g for 15 minutes at 4°C |
| Hemolysis Index | Non-hemolyzed or as specified |
| Platelet Status | Platelet-poor unless otherwise specified |
| Volume Options | 0.5 mL, 1 mL, 5 mL, or custom |
| Storage Temperature | '-20°C or -80°C |
| Shipping | Dry ice |
| Donor Information | Age, sex, and health status available |
Geographic Origins Guide
Select the optimal origin for your research requirements
Chinese Origin ★ MOST COMMON
mainland
Chinese-origin cynomolgus are no longer exported by China. Cynomolgus macaques are not native to China and were historically imported from Cambodia, Vietnam, Laos, and Indonesia. Current samples are sourced from US breeding colonies established from China-line imports.
Mauritian Origin ★ DEFINED GENETICS
island
Mauritian cynomolgus have limited MHC diversity due to founder effects, making them valuable for immunology studies requiring genetic consistency.
Cambodian Origin ★ SOUTHEAST ASIAN
mainland
Cambodian-origin animals offer a Southeast Asian source with genetics that have not been mixed with other country lineages in the same way seen in some China-line populations.
Vietnamese Origin ★ SOUTHEAST ASIAN
mainland
Vietnamese cynomolgus provide another Southeast Asian option for programs that require distinct lineage sourcing or supply chain diversification.
Indonesian Origin ★ ISLAND ORIGIN
island
Indonesian-origin cynomolgus were among the earliest origins used in preclinical research and represented one of the largest research populations before China entered the market.
Philippine Origin ★ ISLAND ORIGIN
island
Philippine-origin cynomolgus were one of the first origins used broadly in research, with a long history as a trusted and widely used model.
Need help selecting an origin?
Our scientific team can advise on the optimal origin for your study design and regulatory requirements.
Serum is obtained from clotted blood without anticoagulant, lacking clotting factors. Plasma is obtained from anticoagulated blood and contains clotting factors. Choose serum for most immunoassays and clinical chemistry; choose plasma for coagulation studies or when clotting factors are relevant.
Store at -20°C for short-term (weeks) or -80°C for long-term storage. Avoid repeated freeze-thaw cycles as this can degrade proteins and affect assay results. Aliquot into single-use volumes upon receipt.
Lipemic serum appears cloudy due to high lipid content, which can interfere with certain assays. Hemolyzed serum has red discoloration from lysed red blood cells. We offer both normal and intentionally lipemic/hemolyzed samples for matrix interference testing.