Cynomolgus Monkey Urine
Cynomolgus Monkey biological fluid sample (Macaca fascicularis) collected under controlled conditions. Processed promptly for optimal quality. Contact us for specifications and availability.
Cynomolgus Monkey Urine Overview
Cynomolgus Monkey Urine is research-grade cynomolgus macaque urine intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information and handling details to support consistency across studies.
Urine provides a non-invasive matrix for renal function assessment, metabolite profiling, and urinary biomarker research.
Common applications
- Renal toxicity and nephrotoxicity studies
- Urinary biomarker discovery
- Drug metabolite identification
- Clinical chemistry and urinalysis
- Kidney function and clearance studies
Collection, processing & handling
Samples are collected and processed using standardized protocols appropriate to the sample type. Packaging and shipping are configured for temperature-controlled logistics to preserve sample integrity for your specific workflow requirements.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Also available: matched serum or plasma for systemic correlation from the same species for comprehensive study design.
Ordering notes
For specific donor criteria, source, volumes, or custom handling requirements, request a quote and include your study specifications. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
About the Cynomolgus Monkey
Macaca fascicularis
The cynomolgus macaque is the most widely used non-human primate in biomedical research, valued for its close physiological and immunological similarity to humans.
With over 60% genetic homology for key immune receptors, cynomolgus monkeys provide highly translatable data for drug development, making them ideal for immunology, infectious disease, and toxicology studies.
Human Similarity
~93% genetic homology with extensive immune receptor cross-reactivity
Global Availability
Multiple geographic origins with established breeding colonies
Regulatory Accepted
FDA & EMA preferred species for biologics safety assessment
Origin Lineages at a Glance
Primary Research Areas
Renal Drug Safety & Toxicology
Measure urinary biomarkers (KIM-1, NGAL, clusterin, albumin) for nephrotoxicity assessment in preclinical safety studies.
Renal Pharmacokinetics
Determine drug and metabolite concentrations in urine for renal clearance and excretion pathway studies.
Kidney Biomarker Discovery
Identify novel urinary protein, metabolite, or exosome biomarkers for acute and chronic kidney injury models.
Metabolomics & Systems Biology
Profile the urinary metabolome for systemic disease models, nutrition studies, and drug metabolism research.
Reproductive & Endocrine Research
Monitor hormone metabolites (cortisol, catecholamines, steroid hormones) via non-invasive urine collection.
| Species | Cynomolgus Monkey (Macaca fascicularis) |
|---|---|
| Sample Type | Urine |
| Collection Method | Metabolism cage collection (timed), catheterization, or cystocentesis under anesthesia |
| Appearance | Clear to slightly yellow; turbid samples noted |
| Typical Yield | 5-50 mL per collection (species and duration-dependent) |
| Volume Options | 1 mL, 5 mL, 10 mL, or custom |
| Collection Duration | Spot, 4-hour, 8-hour, 16-hour, or 24-hour collections available |
| Processing | Centrifuged to remove cellular debris, aliquoted, preservative-free unless specified |
| Storage Temperature | '-80°C |
| Shipping | Dry ice |
| Donor Information | Age, sex, and health status available |
Geographic Origins Guide
Select the optimal origin for your research requirements
Chinese Origin ★ MOST COMMON
mainland
Chinese-origin cynomolgus are no longer exported by China. Cynomolgus macaques are not native to China and were historically imported from Cambodia, Vietnam, Laos, and Indonesia. Current samples are sourced from US breeding colonies established from China-line imports.
Mauritian Origin ★ DEFINED GENETICS
island
Mauritian cynomolgus have limited MHC diversity due to founder effects, making them valuable for immunology studies requiring genetic consistency.
Cambodian Origin ★ SOUTHEAST ASIAN
mainland
Cambodian-origin animals offer a Southeast Asian source with genetics that have not been mixed with other country lineages in the same way seen in some China-line populations.
Vietnamese Origin ★ SOUTHEAST ASIAN
mainland
Vietnamese cynomolgus provide another Southeast Asian option for programs that require distinct lineage sourcing or supply chain diversification.
Indonesian Origin ★ ISLAND ORIGIN
island
Indonesian-origin cynomolgus were among the earliest origins used in preclinical research and represented one of the largest research populations before China entered the market.
Philippine Origin ★ ISLAND ORIGIN
island
Philippine-origin cynomolgus were one of the first origins used broadly in research, with a long history as a trusted and widely used model.
Need help selecting an origin?
Our scientific team can advise on the optimal origin for your study design and regulatory requirements.
Urine is collected via metabolism cage (most common for timed collections), urinary catheterization under sedation, or cystocentesis for sterile samples. Metabolism cage collections can be timed (4h, 8h, 16h, 24h) and are non-invasive. Preservatives can be added upon request.
Volume depends on species, hydration status, and collection duration. Primate spot collections typically yield 5-20 mL. Timed 24-hour collections yield 20-100+ mL depending on species. Custom volumes and pooled samples are available on request.
Urine is evaluated for clarity, color, and absence of gross contamination (feces, food). Samples are centrifuged to remove cellular debris. Standard documentation includes collection duration, volume, and any preservatives used. pH and specific gravity data available on request.