Marmoset CD34+ Cells
Marmoset primary cells (Callithrix jacchus) isolated using validated methods. Available fresh or cryopreserved with viability guarantee. Contact us for cell-specific specifications.
Marmoset CD34+ Cells Overview
Marmoset CD34+ Cells are primary hematopoietic stem and progenitor cells (HSPCs) isolated from common marmoset (Callithrix jacchus) bone marrow. The marmoset is an increasingly important NHP model for gene therapy, neuroscience, and regenerative medicine due to its small size, short generation time, and genetic tractability.
Common Applications
- Gene therapy vector transduction and engraftment studies
- Hematopoietic stem cell transplant modeling
- Colony-forming unit (CFU) assays
- Xenotransplantation and chimera studies
Product Details
Cells are enriched by immunomagnetic CD34 selection from bone marrow aspirates and cryopreserved. Each lot ships with a Certificate of Analysis documenting viability, purity, and donor information. Available in 100K, 0.5M, and 1M cell counts.
About the Marmoset
Callithrix jacchus
Common marmosets are small New World primates increasingly used in neuroscience and aging research.
Their small size, short lifespan, and twinning make them ideal for developmental studies, gene therapy research, and as transgenic models.
Human Similarity
~93% genetic homology with extensive immune receptor cross-reactivity
Global Availability
Multiple geographic origins with established breeding colonies
Regulatory Accepted
FDA & EMA preferred species for biologics safety assessment
Origin Lineages at a Glance
Primary Research Areas
Immunotoxicology Studies
Assess potential immunotoxic effects of drug candidates on immune cell populations and function.
Vaccine Development
Evaluate immunogenicity and T cell responses to vaccine antigens in preclinical models.
CAR-T & Cell Therapy Research
Source material for developing and testing chimeric antigen receptor constructs and adoptive cell therapies.
Cytokine Release Assays
Screen biologics for potential cytokine release syndrome risk using species-relevant immune cells.
Flow Cytometry & Immunophenotyping
Characterize immune cell subset distributions and surface marker expression profiles.
ADCC & CDC Assays
Evaluate antibody-dependent and complement-dependent cytotoxicity of therapeutic antibodies.
| Species | Marmoset (Callithrix jacchus) |
|---|---|
| Cell Type | CD34+ Hematopoietic Stem/Progenitor Cells |
| Cell Count | ≥10 × 10⁶ viable cells per vial (standard) |
| Viability (Fresh) | ≥90% |
| Viability (Post-Thaw) | ≥70% |
| Viability Method | Trypan blue exclusion or flow cytometry |
| Format | Fresh or cryopreserved |
| Cryopreservation Medium | Serum-containing medium with 10% DMSO |
| Isolation Method | Immunomagnetic positive selection (anti-CD34) from mobilized peripheral blood or bone marrow |
| Storage (Cryopreserved) | Liquid nitrogen vapor phase |
| Shipping (Fresh) | Ambient temperature, overnight delivery |
| Shipping (Cryopreserved) | Dry ice |
| Donor Information | Age, sex, and health status available |
| Testing | Pathogen-free per supplier SOPs |
Geographic Origins Guide
Select the optimal origin for your research requirements
South Africa Colony Origin ★ MOST COMMON
captive
Bred in established South African research colonies. Note: this species originated in South America (New World primate lineage).
Need help selecting an origin?
Our scientific team can advise on the optimal origin for your study design and regulatory requirements.
Typical purity is >85% CD34+ cells as assessed by flow cytometry. CD34+ cells are enriched by immunomagnetic positive selection from mobilized peripheral blood or bone marrow. Purity, viability, and colony-forming unit (CFU) data are available.
Yes. CD34+ cells are functional hematopoietic stem/progenitor cells capable of forming CFU-GM, BFU-E, and CFU-GEMM colonies in methylcellulose assays. Colony-forming data from representative lots are available on request.
Thaw rapidly at 37°C, dilute dropwise into pre-warmed StemSpan or equivalent serum-free medium. Centrifuge gently at 200g for 10 minutes. Resuspend and plate immediately for expansion or colony assays. DNase I (10 µg/mL) can be added to reduce clumping.
Post-thaw viability is typically ≥70%. Colony-forming capacity is maintained post-thaw. For optimal engraftment studies, fresh cells are recommended. Viability is assessed by trypan blue exclusion and 7-AAD flow cytometry.
Yes. Donor reservation is available. CD34+ cell yield varies significantly between donors. We can provide cells from G-CSF mobilized donors for higher yields on request.