Rhesus Monkey CD34+ Cells
Rhesus Monkey primary cells (Macaca mulatta) isolated using validated methods. Available fresh or cryopreserved with viability guarantee. Contact us for cell-specific specifications.
The Rhesus Monkey
Macaca mulatta
The rhesus macaque is one of the most studied primate species, fundamental to biomedical research for over a century.
With ~93% genetic homology to humans and extensive immunological characterization, rhesus monkeys are essential for vaccine development, HIV/AIDS research, and neuroscience studies.
Human Similarity
~93% genetic homology with extensive immune receptor cross-reactivity
Global Availability
Multiple geographic origins with established breeding colonies
Regulatory Accepted
FDA & EMA preferred species for biologics safety assessment
Geographic Origins
Common Research Applications
Rhesus Monkey CD34+ Cells are research-grade rhesus macaque primary cells intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information including viability and purity data.
CD34+ hematopoietic stem/progenitor cells enable stem cell research, transplantation studies, and hematopoiesis investigations.
Common applications
- Hematopoietic stem cell research
- Bone marrow transplant modeling
- Gene therapy development
- Hematopoiesis studies
- Engraftment assays
Collection, processing & handling
Samples are collected and processed using standardized protocols appropriate to the sample type. Packaging and shipping are configured for temperature-controlled logistics to preserve sample integrity for your specific workflow requirements.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Ordering notes
For specific donor criteria, source, volumes, or custom handling requirements, request a quote and include your study specifications. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
Immunotoxicology Studies
Assess potential immunotoxic effects of drug candidates on immune cell populations and function.
Vaccine Development
Evaluate immunogenicity and T cell responses to vaccine antigens in preclinical models.
CAR-T & Cell Therapy Research
Source material for developing and testing chimeric antigen receptor constructs and adoptive cell therapies.
Cytokine Release Assays
Screen biologics for potential cytokine release syndrome risk using species-relevant immune cells.
Flow Cytometry & Immunophenotyping
Characterize immune cell subset distributions and surface marker expression profiles.
ADCC & CDC Assays
Evaluate antibody-dependent and complement-dependent cytotoxicity of therapeutic antibodies.
| Species | Rhesus Monkey (Macaca mulatta) |
|---|---|
| Cell Type | CD34+ Hematopoietic Stem/Progenitor Cells |
| Cell Count | ≥10 × 10⁶ viable cells per vial (standard) |
| Viability (Fresh) | ≥90% |
| Viability (Post-Thaw) | ≥70% |
| Viability Method | Trypan blue exclusion or flow cytometry |
| Format | Fresh or cryopreserved |
| Cryopreservation Medium | Serum-containing medium with 10% DMSO |
| Isolation Method | Immunomagnetic positive selection (anti-CD34) from mobilized peripheral blood or bone marrow |
| Storage (Cryopreserved) | Liquid nitrogen vapor phase |
| Shipping (Fresh) | Ambient temperature, overnight delivery |
| Shipping (Cryopreserved) | Dry ice |
| Donor Information | Age, sex, and health status available |
| Testing | Pathogen-free per supplier SOPs |
Geographic Origins Guide
Select the optimal origin for your research requirements
Chinese Origin ★ MOST COMMON
asia
Chinese-origin rhesus are commonly used in toxicology and translational safety programs, supported by established breeding colonies and robust historical datasets.
Indian Origin
india lineage
Indian-origin rhesus represent a historically important research lineage, maintained through domestic breeding programs with strong legacy use in biomedical studies.
Need help selecting an origin?
Our scientific team can advise on the optimal origin for your study design and regulatory requirements.
Typical purity is >85% CD34+ cells as assessed by flow cytometry. CD34+ cells are enriched by immunomagnetic positive selection from mobilized peripheral blood or bone marrow. Purity, viability, and colony-forming unit (CFU) data are available.
Yes. CD34+ cells are functional hematopoietic stem/progenitor cells capable of forming CFU-GM, BFU-E, and CFU-GEMM colonies in methylcellulose assays. Colony-forming data from representative lots are available on request.
Thaw rapidly at 37°C, dilute dropwise into pre-warmed StemSpan or equivalent serum-free medium. Centrifuge gently at 200g for 10 minutes. Resuspend and plate immediately for expansion or colony assays. DNase I (10 µg/mL) can be added to reduce clumping.
Post-thaw viability is typically ≥70%. Colony-forming capacity is maintained post-thaw. For optimal engraftment studies, fresh cells are recommended. Viability is assessed by trypan blue exclusion and 7-AAD flow cytometry.
Yes. Donor reservation is available. CD34+ cell yield varies significantly between donors. We can provide cells from G-CSF mobilized donors for higher yields on request.