Rhesus Monkey Dermal Fibroblasts
Rhesus Monkey primary cells (Macaca mulatta) isolated using validated methods. Available fresh or cryopreserved with viability guarantee. Contact us for cell-specific specifications.
The Rhesus Monkey
Macaca mulatta
The rhesus macaque is one of the most studied primate species, fundamental to biomedical research for over a century.
With ~93% genetic homology to humans and extensive immunological characterization, rhesus monkeys are essential for vaccine development, HIV/AIDS research, and neuroscience studies.
Human Similarity
~93% genetic homology with extensive immune receptor cross-reactivity
Global Availability
Multiple geographic origins with established breeding colonies
Regulatory Accepted
FDA & EMA preferred species for biologics safety assessment
Geographic Origins
Common Research Applications
Rhesus Monkey Dermal Fibroblasts is research-grade rhesus macaque dermal fibroblasts intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information and handling details to support consistency across studies.
Common applications
- Preclinical and translational research
- Assay development and validation
- Biomarker studies
- Method development
Collection, processing & handling
Samples are collected and processed using standardized protocols appropriate to the sample type. Packaging and shipping are configured for temperature-controlled logistics to preserve sample integrity for your specific workflow requirements.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Ordering notes
For specific donor criteria, source, volumes, or custom handling requirements, request a quote and include your study specifications. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
Immunotoxicology Studies
Assess potential immunotoxic effects of drug candidates on immune cell populations and function.
Vaccine Development
Evaluate immunogenicity and T cell responses to vaccine antigens in preclinical models.
CAR-T & Cell Therapy Research
Source material for developing and testing chimeric antigen receptor constructs and adoptive cell therapies.
Cytokine Release Assays
Screen biologics for potential cytokine release syndrome risk using species-relevant immune cells.
Flow Cytometry & Immunophenotyping
Characterize immune cell subset distributions and surface marker expression profiles.
ADCC & CDC Assays
Evaluate antibody-dependent and complement-dependent cytotoxicity of therapeutic antibodies.
| Species | Rhesus Monkey (Macaca mulatta) |
|---|---|
| Cell Type | Dermal Fibroblasts |
| Cell Count | ≥10 × 10⁶ viable cells per vial (standard) |
| Viability (Fresh) | ≥90% |
| Viability (Post-Thaw) | ≥70% |
| Viability Method | Trypan blue exclusion or flow cytometry |
| Format | Fresh or cryopreserved |
| Cryopreservation Medium | Fibroblast medium (DMEM + 10% FBS) with 10% DMSO |
| Isolation Method | Enzymatic digestion (collagenase) of dermis tissue or explant culture outgrowth |
| Storage (Cryopreserved) | Liquid nitrogen vapor phase |
| Shipping (Fresh) | Ambient temperature, overnight delivery |
| Shipping (Cryopreserved) | Dry ice |
| Donor Information | Age, sex, and health status available |
| Testing | Pathogen-free per supplier SOPs |
Geographic Origins Guide
Select the optimal origin for your research requirements
Chinese Origin ★ MOST COMMON
asia
Chinese-origin rhesus are commonly used in toxicology and translational safety programs, supported by established breeding colonies and robust historical datasets.
Indian Origin
india lineage
Indian-origin rhesus represent a historically important research lineage, maintained through domestic breeding programs with strong legacy use in biomedical studies.
Need help selecting an origin?
Our scientific team can advise on the optimal origin for your study design and regulatory requirements.
Primary cells are typically provided at passage 0 (P0) or passage 1 (P1) unless otherwise specified. Low-passage cells retain tissue-specific phenotype and function. Higher passage cells are available on request for applications where passage number is less critical.
Culture conditions vary by cell type. We provide cell-type-specific culture medium recommendations and handling protocols with each order. In general, primary cells require specialized media with appropriate growth factors and supplements. Contact us for detailed protocols.
Thaw rapidly at 37°C, transfer into pre-warmed cell-type-specific medium. Plate immediately onto appropriate substrate (collagen, fibronectin, or gelatin coating as appropriate). Change medium after 24 hours to remove DMSO and non-adherent cells.
Post-thaw viability is typically ≥70% for cryopreserved primary cells. Plating efficiency and time to confluence vary by cell type. Fresh cells generally provide the best plating efficiency and are recommended for sensitive applications.
Yes. Donor demographics (age, sex, health status) and tissue source details are available. Custom tissue dissection and cell isolation can be arranged. Matched sets from the same donor are available on request.