Rhesus Monkey Pan T Cells
Purified Rhesus Monkey Pan T Cells (Macaca mulatta) isolated by immunomagnetic selection. High purity for T cell activation assays, immunotherapy research, and checkpoint inhibitor studies.
Rhesus Monkey Pan T Cells Overview
Rhesus Monkey Pan T Cells are research-grade rhesus macaque primary cells intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information including viability and purity data.
Pan T cells provide a purified T lymphocyte population for adaptive immunity research and T cell-directed therapies.
Common applications
- T cell activation and proliferation
- Adoptive cell therapy development
- T cell receptor studies
- Immunomodulator screening
- Vaccine immunology
Collection, processing & handling
Samples are collected and processed using standardized protocols appropriate to the sample type. Packaging and shipping are configured for temperature-controlled logistics to preserve sample integrity for your specific workflow requirements.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Ordering notes
For specific donor criteria, source, volumes, or custom handling requirements, request a quote and include your study specifications. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
About the Rhesus Monkey
Macaca mulatta
The rhesus macaque is one of the most studied primate species, fundamental to biomedical research for over a century.
With ~93% genetic homology to humans and extensive immunological characterization, rhesus monkeys are essential for vaccine development, HIV/AIDS research, and neuroscience studies.
Human Similarity
~93% genetic homology with extensive immune receptor cross-reactivity
Global Availability
Multiple geographic origins with established breeding colonies
Regulatory Accepted
FDA & EMA preferred species for biologics safety assessment
Origin Lineages at a Glance
Primary Research Areas
T Cell Activation Assays
Measure T cell proliferation, activation markers, and cytokine production.
Immunomodulator Screening
Evaluate effects of immunomodulatory compounds on T cell function.
Checkpoint Inhibitor Research
Study PD-1, CTLA-4, and other checkpoint pathways in relevant species.
CAR-T Development
Source material for chimeric antigen receptor T cell engineering.
Regulatory T Cell Studies
Investigate Treg biology and immunosuppressive mechanisms.
Antigen-Specific Responses
Measure T cell responses to specific antigens and peptides.
| Species | Rhesus Monkey (Macaca mulatta) |
|---|---|
| Cell Type | Pan T Cells (CD3+) |
| Cell Count | ≥10 × 10⁶ viable cells per vial (standard) |
| Viability (Fresh) | ≥90% |
| Viability (Post-Thaw) | ≥70% |
| Viability Method | Trypan blue exclusion or flow cytometry |
| Format | Fresh or cryopreserved |
| Cryopreservation Medium | Serum-containing medium with 10% DMSO |
| Isolation Method | PBMC isolation by Ficoll density gradient, followed by immunomagnetic positive selection (anti-CD3) |
| Storage (Cryopreserved) | Liquid nitrogen vapor phase |
| Shipping (Fresh) | Ambient temperature, overnight delivery |
| Shipping (Cryopreserved) | Dry ice |
| Donor Information | Age, sex, and health status available |
| Testing | Pathogen-free per supplier SOPs |
Geographic Origins Guide
Select the optimal origin for your research requirements
Chinese Origin ★ MOST COMMON
asia
Chinese-origin rhesus are commonly used in toxicology and translational safety programs, supported by established breeding colonies and robust historical datasets.
Indian Origin
india lineage
Indian-origin rhesus represent a historically important research lineage, maintained through domestic breeding programs with strong legacy use in biomedical studies.
Need help selecting an origin?
Our scientific team can advise on the optimal origin for your study design and regulatory requirements.
Typical purity is >90% CD3+ T cells as assessed by flow cytometry. Sub-populations (CD4+, CD8+) are further enriched by immunomagnetic positive selection, with purity typically >85-95% depending on the specific marker and species. A Certificate of Analysis with purity data is included with each lot.
Many anti-human CD antibodies cross-react with cynomolgus and rhesus monkey T cell markers, including CD3, CD4, CD8, and CD28. Cross-reactivity varies by clone and species. We can provide guidance on validated antibody clones for your species of interest.
Thaw rapidly in a 37°C water bath until a small ice crystal remains. Transfer dropwise into pre-warmed complete culture medium. Centrifuge at 300g for 10 minutes, aspirate supernatant, and resuspend in fresh medium. Allow 2-4 hours of rest in culture before functional assays for optimal viability and activation response.
Post-thaw viability is typically ≥70% for cryopreserved T cells. Viability is assessed by trypan blue exclusion or flow cytometry (7-AAD/Annexin V). Fresh cells are shipped with viability ≥90%. Recovery and function can be improved with overnight resting before stimulation.
Yes. We support donor reservation, repeat-donor programs, and matched cell sets from the same donor. Donor demographics (age, sex, weight, health status) are available. Contact us with your requirements for custom donor matching.