Sinclair Nanopig Peripheral Blood Mononuclear Cells (PBMC)
Sinclair Minipig whole blood available fresh or processed for hematology and immunology research.
Sinclair Nanopig Peripheral Blood Mononuclear Cells (PBMC) Overview
Sinclair Nanopig Peripheral Blood Mononuclear Cells (PBMC) are research-grade pig peripheral blood mononuclear cells (PBMCs) intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information including viability data, cell counts, and handling details to support consistency across studies.
PBMCs are isolated mononuclear cells including lymphocytes and monocytes, critical for immunological research requiring viable, functional immune cells.
Available fresh or cryopreserved to match your experimental timeline and viability requirements.
Common applications
- T cell and B cell functional assays
- Flow cytometry and immunophenotyping
- Cytokine secretion and ELISpot assays
- Mixed lymphocyte reactions (MLR)
- CAR-T and cell therapy development
- Vaccine immunogenicity studies
Collection, processing & handling
PBMCs are isolated using density gradient separation with standardized protocols appropriate to the donor species. Fresh PBMCs are shipped in validated containers with temperature monitoring; cryopreserved PBMCs are shipped on dry ice with documented freeze-thaw protocols. Viability testing available upon request.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Also available: matched serum or plasma for comprehensive immune profiling from the same species for comprehensive study design.
Ordering notes
For specific donor criteria, source, volumes, or custom handling requirements, request a quote and include your study specifications. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
Sinclair Nanopig Overview
The Sinclair Nanopig is the smallest miniature swine line and is renowned for spontaneously developing cutaneous melanoma that regresses much like human melanoma, providing a unique large-animal model for oncology and dermatology research.
Quick Facts
Hematology Studies
Analyze blood cell populations, morphology, and function.
Immunology Research
Study immune cell populations and responses in whole blood.
Toxicology Assessment
Evaluate hematological effects of drug candidates.
Flow Cytometry
Perform flow cytometric analysis of blood cell populations.
| Species | Sinclair Minipig |
|---|---|
| Sample Type | Whole Blood |
| Health Status | SPF or Conventional |
| Storage | Format-dependent |
| Documentation | Certificate of Analysis, Health Records |
| Quality Control | Visual inspection, viability testing (cells) |
Swine are physiologically similar to humans in cardiovascular, GI, and skin systems, making them valuable translational models for drug development.
Standard products ship within 5-10 business days. Custom requests may require additional time.
Yes, we can accommodate specific collection requirements, processing protocols, and sample sizes.
Yes, multiple sample types from single donors can be arranged for comprehensive studies.