Sprague Dawley Rat Bone Marrow Mononuclear Cells
Sprague Dawley Rat (Rattus norvegicus) cell product collected under controlled conditions. Processed promptly for optimal quality. Contact us for specifications and availability.
Sprague Dawley Rat Bone Marrow Mononuclear Cells Overview
Sprague Dawley Rat Bone Marrow Mononuclear Cells is research-grade rat bone marrow intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information and handling details to support consistency across studies.
Bone marrow provides access to hematopoietic stem cells and progenitor populations essential for hematology, oncology, and regenerative medicine research.
Common applications
- Hematopoietic stem cell (HSC) research
- Colony-forming unit (CFU) assays
- Bone marrow transplant modeling
- Hematological malignancy studies
- Myeloid and lymphoid differentiation research
Collection, processing & handling
Bone marrow is collected via aspiration with documented protocols. Available as whole aspirate, mononuclear cell preparations, or processed fractions. Shipped fresh or cryopreserved depending on downstream application requirements.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Also available: matched peripheral blood for comparative hematopoiesis studies from the same species for comprehensive study design.
Ordering notes
For specific donor criteria, strain, volumes, or custom handling requirements, request a quote and include your study specifications. Available strains include Sprague Dawley and Wistar. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
Sprague Dawley Rat Overview
The Sprague Dawley is an outbred albino rat and the most widely used rat strain in pharmacology, toxicology, and safety testing. Its calm temperament, rapid growth, and extensive historical control data make it a regulatory mainstay.
Quick Facts
Hematopoiesis Studies
Investigate bone marrow cell development and differentiation.
Stem Cell Research
Study hematopoietic stem and progenitor cell biology.
Colony Forming Assays
Assess progenitor potential through CFU assays.
Immunophenotyping
Characterize bone marrow cell populations by flow cytometry.
Drug Screening
Evaluate myelotoxicity and effects on hematopoiesis.
Transplantation Studies
Bone marrow reconstitution and engraftment research.
| Species | Sprague Dawley Rat (Rattus norvegicus) |
|---|---|
| Cell Type | Bone Marrow Mononuclear Cells |
| Source | Femur and tibia |
| Isolation Method | Density gradient centrifugation |
| Viability | >90% (typical) |
| Storage | Fresh or cryopreserved |
Bone marrow is typically harvested from femurs and tibias for maximum yield.
Typical yield is 50-100 million MNCs per rat from combined leg bones.
Yes, bone marrow MNCs contain hematopoietic progenitors including CD34+ cells.
Yes, we can provide unfractionated bone marrow or MNCs as needed.