Sprague Dawley Rat CD14+ Monocytes
Sprague Dawley Rat (Rattus norvegicus) cell product collected under controlled conditions. Processed promptly for optimal quality. Contact us for specifications and availability.
Sprague Dawley Rat CD14+ Monocytes Overview
Sprague Dawley Rat CD14+ Monocytes are research-grade rat primary cells intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information including viability and purity data.
CD14+ monocytes are innate immune cells that differentiate into macrophages and dendritic cells, supporting inflammation and phagocytosis research.
Common applications
- Monocyte-to-macrophage differentiation
- Dendritic cell generation
- Inflammation research
- Phagocytosis assays
- Innate immunity studies
Collection, processing & handling
Samples are collected and processed using standardized protocols appropriate to the sample type. Packaging and shipping are configured for temperature-controlled logistics to preserve sample integrity for your specific workflow requirements.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Ordering notes
For specific donor criteria, strain, volumes, or custom handling requirements, request a quote and include your study specifications. Available strains include Sprague Dawley and Wistar. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
Sprague Dawley Rat Overview
The Sprague Dawley is an outbred albino rat and the most widely used rat strain in pharmacology, toxicology, and safety testing. Its calm temperament, rapid growth, and extensive historical control data make it a regulatory mainstay.
Quick Facts
Macrophage Differentiation
Generate monocyte-derived macrophages for functional studies.
Dendritic Cell Generation
Differentiate monocytes into dendritic cells for immunology research.
Phagocytosis Assays
Assess monocyte/macrophage phagocytic function.
Inflammation Studies
Investigate monocyte activation and cytokine production.
Drug Screening
Evaluate drug effects on monocyte function and differentiation.
Immunophenotyping
Characterize monocyte subsets and activation states.
| Species | Sprague Dawley Rat (Rattus norvegicus) |
|---|---|
| Cell Type | Monocytes (CD14+) |
| Source | Peripheral blood |
| Isolation Method | Immunomagnetic positive selection |
| Purity | >90% (typical) |
| Viability | >90% (typical) |
Yes, monocytes can be differentiated using M-CSF or GM-CSF protocols.
Culture in RPMI with 10% FBS and 50ng/mL M-CSF for 5-7 days for macrophage differentiation.
Contact us for specific monocyte subset requirements.
Monocytes represent 5-10% of PBMCs. Yields vary based on animal and isolation method.