Sprague Dawley Rat NK Cells
Sprague Dawley Rat (Rattus norvegicus) cell product collected under controlled conditions. Processed promptly for optimal quality. Contact us for specifications and availability.
Sprague Dawley Rat Overview
The Sprague Dawley is an outbred albino rat and the most widely used rat strain in pharmacology, toxicology, and safety testing. Its calm temperament, rapid growth, and extensive historical control data make it a regulatory mainstay.
Quick Facts
Sprague Dawley Rat NK Cells are research-grade rat primary cells intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information including viability and purity data.
Natural killer (NK) cells are innate immune effectors critical for cancer immunotherapy research and viral immunity studies.
Common applications
- Cancer immunotherapy development
- NK cell-mediated cytotoxicity
- Viral immunity research
- Antibody-dependent cellular cytotoxicity (ADCC)
- Innate immune profiling
Collection, processing & handling
Samples are collected and processed using standardized protocols appropriate to the sample type. Packaging and shipping are configured for temperature-controlled logistics to preserve sample integrity for your specific workflow requirements.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Ordering notes
For specific donor criteria, strain, volumes, or custom handling requirements, request a quote and include your study specifications. Available strains include Sprague Dawley and Wistar. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
Cytotoxicity Assays
Assess natural killer cell-mediated killing of target cells.
Immunophenotyping
Characterize NK cell subsets and activation markers.
ADCC Studies
Evaluate antibody-dependent cellular cytotoxicity for therapeutic antibody development.
Cancer Immunotherapy
Support NK cell-based immunotherapy research.
Cytokine Studies
Measure NK cell cytokine production including IFN-gamma and TNF-alpha.
Drug Screening
Evaluate drug effects on NK cell function and viability.
| Species | Sprague Dawley Rat (Rattus norvegicus) |
|---|---|
| Cell Type | Natural Killer Cells |
| Source | Peripheral blood or spleen |
| Isolation Method | Immunomagnetic selection |
| Purity | >85% (typical) |
| Viability | >90% (typical) |
Rat NK cells are typically identified as CD3-negative, NKR-P1A+ (CD161+) or CD56+ populations.
Yes, we can provide freshly isolated NK cells for immediate use in functional assays.
RPMI 1640 with 10% FBS and IL-2 supplementation for maintenance and expansion.
Yes, we can provide IL-2 activated NK cells upon request.