Sprague Dawley Rat Tonsil Mononuclear Cells (MNCs)
Sprague Dawley Rat (Rattus norvegicus) cell product collected under controlled conditions. Processed promptly for optimal quality. Contact us for specifications and availability.
Sprague Dawley Rat Tonsil Mononuclear Cells (MNCs) Overview
Sprague Dawley Rat Tonsil Mononuclear Cells (MNCs) are research-grade rat primary cells intended for preclinical and translational research. Each order includes a Certificate of Analysis (COA) with lot-specific information including viability and purity data.
Tonsil-derived mononuclear cells provide access to mucosal immune populations for respiratory immunology research.
Common applications
- Mucosal immunity research
- B cell biology
- Germinal center studies
- Respiratory immunology
- Oral vaccine development
Collection, processing & handling
Samples are collected and processed using standardized protocols appropriate to the sample type. Packaging and shipping are configured for temperature-controlled logistics to preserve sample integrity for your specific workflow requirements.
Quality control & documentation
QC testing options available on request, including material-appropriate analytical checks and extended documentation. Standard documentation includes collection/processing metadata, lot identifiers, and chain-of-custody records. Custom QC panels can be configured for GLP or regulatory-facing studies.
Ordering notes
For specific donor criteria, strain, volumes, or custom handling requirements, request a quote and include your study specifications. Available strains include Sprague Dawley and Wistar. We routinely support longitudinal programs, matched sample sets, and custom collection protocols.
Sprague Dawley Rat Overview
The Sprague Dawley is an outbred albino rat and the most widely used rat strain in pharmacology, toxicology, and safety testing. Its calm temperament, rapid growth, and extensive historical control data make it a regulatory mainstay.
Quick Facts
Mucosal Immunology
Study immune responses at mucosal surfaces.
Immunophenotyping
Characterize tonsillar immune cell populations.
Vaccine Research
Evaluate mucosal immune responses to vaccines.
B Cell Studies
Tonsils are rich in B cells for antibody research.
Infection Models
Study responses to respiratory pathogens.
Drug Screening
Evaluate drug effects on mucosal immunity.
| Species | Sprague Dawley Rat (Rattus norvegicus) |
|---|---|
| Cell Type | Tonsil Mononuclear Cells |
| Source | Fresh tonsil tissue |
| Isolation Method | Mechanical dissociation and density gradient |
| Viability | >85% (typical) |
| Storage | Fresh or cryopreserved |
Tonsils contain germinal centers rich in B cells and are better for studying mucosal immunity.
Tonsil MNCs are enriched for B cells and also contain T cells and antigen-presenting cells.
Yield varies but typically 10-50 million cells per rat depending on tonsil size.
Yes, we can isolate B cells or other populations from tonsil MNCs.